Ole Miss vs Tulane: Prediction, Odds, History & Score

In college football, some rivalries stay one-sided for a while. Then they stay one-sided for longer than anyone expects. Ole Miss has not lost to Tulane since 1995 — and heading into their most recent matchup, the Rebels had won 10 straight. That’s the kind of streak that turns a regional game into a story about dominance, and it’s exactly what makes the 2025 chapter worth following.

Head-to-Head Since 2000: Ole Miss 6 wins, Tulane 0 · Most Recent Score: Ole Miss 41-10 Tulane (Dec 20, 2025) · Rivalry Start: December 2, 1893 · Ole Miss CFP Seed: No. 6 · Tulane CFP Seed: No. 11

This comparison table consolidates the most important facts about the Ole Miss-Tulane rivalry for quick reference.

Who is favored to win Tulane vs Ole Miss?

Betting markets have been clear on this matchup for months. Ole Miss entered the December 20, 2025 College Football Playoff First Round game as a significant favorite, with multiple sportsbooks listing the Rebels as 16.5 to 17.5-point favorites against Tulane. CBS Sports listed Ole Miss as 17-point favorites with an over/under of 57.5, while FOX Sports gave the Rebels a 90.2% implied win probability based on the moneyline odds.

Current odds and picks

The line movement from regular season to playoff tells its own story. FanDuel had Ole Miss favored by 12.5 points when the teams met in the regular season on September 20, 2025, with a moneyline of -429 and a total of 61.5. By the time the CFP matchup arrived, the spread had widened to 16.5-17.5 points, with the total dropping to 57.5. Sports Illustrated reported early CFP odds of Ole Miss -17.5, Tulane +17.5.

The implied probability of 90.2% from FOX Sports reflects not just the point spread but also Tulane’s position as the No. 11 seed facing the No. 6 seed on the road at Vaught-Hemingway Stadium, where Ole Miss went 9-0 at home during the 2025 regular season.

Key player matchups

While detailed player statistics from the December 20 game remain limited in the immediate post-game data, the matchup featured Tulane’s offense against Ole Miss’s defense. Tulane entered the CFP game with a 4-3 road record, having faced challenging environments throughout the season. The Green Wave’s ability to move the ball against an Ole Miss defense that had been dominant at home will be a key factor if these teams meet again.

Ole Miss vs. Tulane Prediction, Odds, Picks – December 20, 2025

The College Football Playoff First Round matchup between Ole Miss and Tulane tipped off at 3:30 p.m. ET on December 20, 2025, at Vaught-Hemingway Stadium in Oxford, Mississippi. The game aired on TNT and truTV as part of the CFP broadcast package.

Betting lines

Multiple sportsbooks aligned on the odds for this game. CBS Sports set Ole Miss as 17-point favorites with a total of 57.5, while FOX Sports reported a range of 16.5 to 17.5 points favoring the Rebels. The over/under sat at 57.5 across most books, reflecting an expectation that Ole Miss would score early and often.

The quarter-by-quarter box score from ESPN showed Tulane scoring 0-3-0-7 by quarters, while Ole Miss posted 14-3-10-14. That pattern — a slow start for both teams in the second quarter, followed by Ole Miss pulling away in the third and fourth — matched the betting total staying relatively close despite the final margin.

Expert analysis

FOX Sports analysts gave Ole Miss a 90.2% implied win probability heading into the game, one of the highest favorites in the first round of the 2025 CFP. However, College Football News writer Pete Fiutak noted that Tulane had the talent to “trip up a Rebel team that might be looking toward next week” — suggesting the upset potential was real despite the odds.

The Green Wave have the talent to trip up a Rebel team that might be looking toward next week.

— Pete Fiutak, College Football News

The final score of 41-10 fell within the betting range, with Ole Miss covering the spread and the total going under at 51 combined points. Tulane managed only one offensive touchdown in the fourth quarter after the game was effectively decided.

Has Tulane beat Ole Miss?

The short answer is no — not in recent memory, and not in the College Football Playoff era. Ole Miss leads the all-time series decisively, and the Green Wave’s last victory over the Rebels came in the 1990s. The 41-10 playoff loss on December 20, 2025, extended a remarkable streak that dates back more than 25 years.

Head-to-head record

Ole Miss Athletics confirms that the Rebels lead the series 10-0 in the last 10 matchups from 1995 to 2025. The first-ever meeting between the schools occurred on December 2, 1893, with Ole Miss winning 12-4. Since then, the Rebels have dominated the rivalry, winning by margins ranging from single digits to 50 points.

The largest margin of victory in series history came on October 18, 1957, when Ole Miss defeated Tulane 50-0. That 50-point shutout remains one of the most lopsided results in the history of the rivalry.

Recent games

The 2025 season featured two meetings between the schools. The regular season matchup on September 20, 2025, served as SEC Week 4 action, with Ole Miss entering as 12.5-point favorites at FanDuel. The second meeting came in the CFP First Round on December 20, where the stakes — and the margin — were higher.

In both 2025 games, Ole Miss controlled the outcome from start to finish. The September game set the tone for the season, and the playoff rematch confirmed that Tulane had not narrowed the gap. Tulane’s final record of 11-3 reflects a strong season by any measure — just not strong enough to break through against the Rebels.

Ole Miss vs Tulane football history

The Ole Miss-Tulane football rivalry stretches back over 130 years, beginning with a 12-4 Ole Miss victory on December 2, 1893. What began as a regional matchup between two programs in the Deep South has evolved into a sporadic but consistently one-sided rivalry, with Ole Miss holding a decisive historical advantage.

Rivalry origins

The earliest games between Ole Miss and Tulane reflected the geography and conference alignment of the era. Both programs were regional powers in the South, and the matchups drew significant local interest. Winsipedia provides complete game-by-game results for the series, documenting each meeting from 1893 through the present day.

The rivalry’s modern era has been defined by Ole Miss dominance. While the teams have not met every season — scheduling conflicts and conference realignment have affected frequency — the results when they have played have been remarkably consistent in their outcome.

Notable games

Beyond the December 20, 2025 CFP game, several dates stand out in the rivalry’s history. The 50-0 shutout on October 18, 1957, remains the largest margin of victory in series history. The 2025 season added two new data points: a regular season game on September 20 and the playoff matchup on December 20.

The December 20 game marked the first-ever College Football Playoff meeting between the schools, adding a new dimension to a rivalry that had previously been confined to regular season or bowl play. With Ole Miss as the No. 6 seed and Tulane as the No. 11 seed, the playoff format ensured a high-stakes matchup that drew national attention.

Ole Miss vs Tulane tickets, date and odds

For fans looking to attend or follow the Ole Miss-Tulane matchup, the December 20, 2025 CFP First Round game provided the most recent opportunity. The game kicked off at 3:30 p.m. ET and was broadcast nationally on TNT and truTV, making it accessible to viewers beyond those who could attend in person at Vaught-Hemingway Stadium.

Game date and live updates

The December 20, 2025 date came after the teams first met in the regular season on September 20, 2025. That regular season game served as SEC Week 4 action and was available through live odds tracking on platforms like Action Network, which monitored betting lines and score updates in real time throughout the game.

For future matchups, scheduling typically depends on conference rotation and potential non-conference agreements. Tulane plays in the American Athletic Conference while Ole Miss competes in the SEC, meaning the teams do not share an annual conference matchup and must schedule each other separately.

Ticket info

The December 20 game was played at Vaught-Hemingway Stadium in Oxford, Mississippi, where Ole Miss posted a 9-0 home record during the 2025 regular season. Ticket demand for CFP games typically exceeds supply, with priority given to season ticket holders and alumni associations before public sales.

For the regular season meeting on September 20, tickets were available through both teams’ athletic departments and secondary market platforms. The game represented one of the higher-profile non-conference matchups of the season, drawing interest from both fan bases.

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Ole Miss carries momentum from their recent 28-10 win over Georgia Bulldogs into this Tulane clash, where history favors the Rebels heavily.

Frequently asked questions